Preheat the oven to 350°F and line a baking sheet with parchment paper.
Blend the cottage cheese, egg, honey, melted butter, vanilla extract, and orange zest until smooth.
Whisk the vanilla protein powder, all-purpose flour, oat flour, baking powder, and salt together.
Stir the blended cottage cheese mixture into the dry ingredients until a soft dough forms.
Fold in the pistachios and dried cranberries. Chill the dough for 25 minutes.
Scoop 12 portions onto the baking sheet and flatten them slightly with the back of a spoon.
Bake for 12 to 14 minutes, until the edges are golden and the centers are set. Cool for 10 minutes before transferring the cookies to a rack.